VS 2010 not recognizing Panda or Hydra

I made some tweaks to my Panda II and Hydra code and wanted to deploy them but Visual Studio 2010 won’t see either board.
I had issues with my Hydra on one machine that never were resolved, but it did work on my Surface (https://www.ghielectronics.com/community/forum/topic?id=14689) but VS on the Surface isn’t seeing the Hydra anymore.
I’ve tried 2 different Windows 8 machines. Both machines can ping both devices using MFDeploy and FEZConfig. I’ve got NET MF 4.2 QFE2 and Net MF 4.1 installed on both.

I brought my Panda in to work today and VS was able to deploy the project from a Windows 7 x64 machine.