Did you try to change the COM-Port number inside the … hmmm… “Device-Manager” in your windows system ?
(Sorry, I only have a german windows. I don’t know the exact name in English windows and my English is… you can read it :-[ )
Can you connect to your device with a normal terminal program ?
(If you need to send some character sequences I prefer “docklight terminal” which has programmable buttons)
Do you have a tool to take a look at the serial lines (LED adapter or something else ) ?
No need to see every single bit, but blinking LEDs are very useful for a first check.
Do you have a second COM-Port and a adapter cable (in german its called “Null-Modem-Kabel”) to connect both COM-Ports and check your program output with a terminal program?
ask google for “rs232 spy cable” !
There are some schematics for a spy adapter. I am always using this sort of adapter (with additional LEDs) if I need to program and test a serial connection.