Is SPI needed when using the 3.5 Inch Touch Display

I see that GHI offers the 3.5 Inch Touch Display

Since they cut and pasted parts of the actual data sheet there rather than just giving the full data sheet it is not clear to me if its used in 24bit RGB mode do we still need to use the SPI register interface to set up any registers.

Can we simply use it by giving it RGB data along with Hsync, Vsync, PCLK & DE signals ?

@ andre.m

Thank you!