Do you mean that you are going to place the USBizi chip that is used on Domino to make your own board and expose all pins? How are you going to get to all pins on Domino?
The domino/rhino also has more supporting things on the board design. Like a part that handles reset better. Things like that did not make it on the economic panda. Thats also ignoring usb host and the sd card and so on.