I have had this issue as long as I can remember, but for whatever the reason I haven’t really ever though to speak up about it.
Basically, every time I deploy to my Domino there is always some issue. The most common issue is that VS will not be able to reboot the Domino – I have to manually reset it. Other times, the debugger will fail for various other reasons. Sometimes it just says there is an issue with my hardware.
This happens CONSTANTLY and it’s only now that it has really gotten on my nerves.
Chris Walker pointed out that the reason why this is happening might be due to the fact that I have a high end computer that is jumping against some timeout. For the record, I have these issues with my Netduinos too, and deploying from my slower computers works fine.